alli. If you have the will, we have the power.™ real weight loss begins with you. If you've tried everything and are serious about weight loss, you may be ready for the alli program. alli is the only FDA approved, over-the-counter weight loss product to help you lose 50% more weight than with dieting alone. so, if you could lose 10 pounds with dieting, you could lose 15 pounds with alli.